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Article

IQGAPs in cancer: A family of scaffold proteins underlying tumorigenesis

9 May 2009

Abstract excerpt

The IQGAP family comprises three proteins in humans. The best characterized is IQGAP1, which participates in protein-protein interactions and integrates diverse signaling pathways. IQGAP2 and IQGAP3 harbor all the domains identified in IQGAP1, but their biological roles are poorly defined. Proteins that bind IQGAP1 include Cdc42 and Rac1, E-cadherin, beta-catenin, calmodulin and components of the...

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Identifiers

PMID: 19433088
DOI: 10.1016/j.febslet.2009.05.007

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IQGAPs in cancer: A family of scaffold proteins underlying tumorigenesisPMID 19433088Read ↗

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