Article

Role of IQGAP1 in Head and Neck Carcinogenesis

2018-01-24

Abstract excerpt

<h4>ABSTRACT</h4> Head and neck squamous cell carcinoma (HNSCC) is a common cancer in humans. Phosphoinositide 3-kinase (PI3K)/AKT signaling, along with its downstream effector mTOR, is one of the most frequently altered pathways in HNSCC, and is downstream of growth factor signaling including that mediated by epidermal growth factor receptor (EGFR), which is also commonly upregulated in HNSCC. Recently, IQ motif...

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Literature Corpus work: 235bbe42-a967-52e0-848c-6690063d1d9c
DOI: 10.1101/253484

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