Article
Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways.
Journal of clinical pathology - 1 Jun 1999
Jass J R, Biden K G, Cummings M C, Simms L A, Walsh M, Schoch E, Meltzer S J, Wright C, Searle J, Young J, Leggett B A
Abstract excerpt
BACKGROUND: 10% of sporadic colorectal cancers are characterised by a low level of microsatellite instability (MSI-L). These are not thought to differ substantially from microsatelite-stable (MSS) cancers, but MSI-L and MSS cancers are distinguished clinicopathologically and in their spectrum of genetic alterations from cancers showing high level microsatellite instability (MSI-H). AIMS: To study the distribution...
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