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Article

Low level microsatellite instability may be associated with reduced cancer specific survival in sporadic stage C colorectal carcinoma

10 Dec 2004

Abstract excerpt

BACKGROUND: Colorectal cancers (CRCs) may be categorised according to the degree of microsatellite instability (MSI) exhibited, as MSI-high (MSI-H), MSI-low (MSI-L), or microsatellite stable (MSS). MSI-H status confers a survival advantage to patients with sporadic CRC. AIMS: To determine if low levels of MSI are related to the clinicopathological features and prognosis of sporadic stage C CRC. PATIENTS: A total...

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PMID: 15591513
DOI: 10.1136/gut.2003.034579

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