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Article

Molecular profiling of sporadic colorectal tumors by microsatellite analysis.

International journal of oncology - 1 Jan 2000

Gebert J, Sun M, Ridder R, Hinz U, Lehnert T, Möller P, Schackert H K, Herfarth C, von Knebel Doeberitz M

Abstract excerpt

To investigate the prognostic value of multiple genetic alterations, individual molecular tumor profiles were established in 79 sporadic colorectal carcinomas (41 stage II and 38 stage III). Tumors were analyzed for allelic loss (LOH) and genetic instability (MSI) using 14 microsatellites intragenic to or associated with tumor suppressor or DNA mismatch repair genes. Molecular profiling identified tumors with LOH...

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PMID: 10601563

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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