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Article

Microsatellite instability in colorectal cancer: clinicopathological significance

23 Oct 2015

Abstract excerpt

Although often viewed as a single disease, colorectal cancer more accurately represents a constellation of heterogeneous subtypes that result from different combinations of genetic events and epigenetic alterations. Chromosomal instability (CIN), microsatellite instability (MSI) and CpG island methylator phenotype (CIMP) have been identified as the three major molecular characteristics, which interact with other...

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PMID: 26619098
DOI: 10.5114/pjp.2015.54953

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