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Article

Do MSI-L sporadic colorectal tumors develop through "mild mutator pathway"?

American journal of clinical oncology - 1 Aug 2006

Oliart Soledad, Martínez-Santos Cristina, Moreno-Azcoita Mariano, Cerquella Carlos, Nejda Nargisse, Daimiel Lydia, Iglesias Daniel, Fernández-Peralta Antonia M, González-Aguilera Juan J

Abstract excerpt

BACKGROUND: The mutator pathway implied in the development of colorectal cancer (CRC) is characterized by microsatellite instability (MSI). MSI tumors can be subdivided according to the level of instability: MSI-H (high), MSI-L (low) or stable MSS. MSI-H CRC displays a well described distinct phe...

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Identifiers

PMID: 16891863
DOI: 10.1097/01.coc.0000221428.35366.cb

Genes

KRAS
MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16891863-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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