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Article

Microsatellite instability and the clinicopathological features of sporadic colorectal cancer.

Gut - 1 Jun 2001

Ward R, Meagher A, Tomlinson I, O'Connor T, Norrie M, Wu R, Hawkins N

Abstract excerpt

BACKGROUND AND AIMS: In this study, we prospectively examined the clinical significance of the microsatellite instability (MSI) phenotype in sporadic colorectal cancer, and investigated methods for effective identification of these tumours in routine pathology practice. METHODS: DNA was extracted from 310 tumours collected from 302 consecutive individuals undergoing curative surgery for sporadic colorectal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11358903
DOI: 10.1136/gut.48.6.821
PMCID: PMC1728324

Genes

MLH1
MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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