Article
Analysis of APCL, a brain-specific adenomatous polyposis coli homologue, for mutations and expression in brain tumors.
Japanese journal of cancer research : Gann - 1 Sept 1999
Nakagawa H, Koyama K, Monden M, Nakamura Y
Abstract excerpt
We recently identified a novel homologue of the adenomatous polyposis coli (APC) tumor suppressor gene, APCL, whose abundant and specific expression in the central nervous system indicated an important role in neuronal proliferation and differentiation. To investigate possible involvement of APCL alterations in brain tumors, we first analyzed the expression of APCL mRNA in seven glioma tissues by...
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