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Article

High levels of expression of the tumor suppressor gene APC during development of the rat central nervous system

1 May 1994

Abstract excerpt

The adenomatous polyposis coli (APC) gene is a tumor suppressor gene that is mutated in human familial adenomatous polyposis, an autosomal dominant condition with predisposition to colorectal carcinoma and brain tumors. Although tumor suppressor genes appear to play a general role in regulating cellular proliferation, the normal biological function of the APC gene product is unknown. In the present study, we...

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PMID: 8182459
DOI: 10.1523/jneurosci.14-05-03059.1994

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High levels of expression of the tumor suppressor gene APC during development of the rat central nervous systemPMID 8182459Read ↗

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