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Article

IL-4 receptor genetic polymorphisms and asthma in Asian populations.

Respiratory medicine - 1 Jan 2007

Zhang Weidong, Zhang Xiaozhu, Qiu Diwen, Sandford Andrew, Tan Wan C

Abstract excerpt

BACKGROUND: IL-4 receptor alpha chain is crucial for the binding and signaling of IL-4, which mediates isotype switching and IgE production. The gene of IL-4 receptor alpha chain is a candidate gene for asthma and atopy. OBJECTIVES: To determine whether Ile50Val and Q576R polymorphisms of IL-4 receptor alpha chain gene were associated with asthma and higher level of total IgE in Chinese, Malay and Indian...

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Identifiers

PMID: 16757160
DOI: 10.1016/j.rmed.2006.04.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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