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Article

V75R576 IL-4 receptor alpha is associated with allergic asthma and enhanced IL-4 receptor function.

Journal of immunology (Baltimore, Md. : 1950) - 1 Aug 2002

Risma Kimberly A, Wang Ning, Andrews Ryan P, Cunningham Christie M, Ericksen Mark B, Bernstein Jonathan A, Chakraborty Ranajit, Hershey Gurjit K Khurana

Abstract excerpt

Asthma is a complex polygenic disease. Many studies have implicated the importance of IL-4R alpha in the development of allergic inflammation and its gene has been implicated in the genetics of asthma and atopy. In this study, we examined the functional consequences of two of the human IL-4R alpha allelic variants that have been found to associate with asthma and atopy. We examined the effects of each variant...

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Source

Identifiers

PMID: 12133990
DOI: 10.4049/jimmunol.169.3.1604

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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