Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A comprehensive analysis of interleukin-4 receptor polymorphisms and their association with atopy and IgE regulation in childhood.

International archives of allergy and immunology - 1 Dec 2004

Woitsch Bernd, Carr David, Stachel Daniel, Schmid Irene, Weiland Stephan K, Fritzsch Christian, von Mutius Erika, Kabesch Michael

Abstract excerpt

BACKGROUND: The interleukin (IL) 4/IL13 pathway is involved in the regulation of IgE production associated with atopic diseases. Numerous polymorphisms have been identified in the coding region of the IL4 receptor alpha chain (IL4Ra) and previous association studies have shown conflicting results. Based on their putative functional role, polymorphisms A148G, T1432C and A1652G, located in the coding region of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma
Share to Child

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Germany

Share to Haplotypes

Share to Polymerase Chain Reaction

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 15564773
DOI: 10.1159/000082326

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A comprehensive analysis of interleukin-4 receptor polymorphisms and their association with atopy and IgE regulation in childhood.PMID 15564773Read ↗

Polymorphisms in the interleukin 4, interleukin 4 receptor and interleukin 13 genes and allergic phenotype: A case control study.Semantic proximity Read ↗

Haplotypes of the interleukin-4 receptor alpha chain gene associate with susceptibility to and severity of atopic asthma.Semantic proximity Read ↗

The R576 IL-4 receptor alpha allele correlates with asthma severity.Semantic proximity Read ↗

IL4RA gene expression in relation to I50V, Q551R and C-3223T polymorphisms.Semantic proximity Read ↗

Gene-gene interaction between interleukin-4 and interleukin-4 receptor alpha in Korean children with asthma.Semantic proximity Read ↗

IL-4 receptor alpha chain genetic polymorphism and total IgE levels in the English population: two-locus haplotypes are more informative than individual SNPs.Semantic proximity Read ↗

Polymorphisms in IL4 and iLARA confer susceptibility to asthma.Semantic proximity Read ↗

Interleukin 4 and Interleukin 4 receptor alpha gene variants and risk of atopy - A case control study based assessment.Semantic proximity Read ↗

Polymorphisms in the interleukin-4 and interleukin-4 receptor alpha chain genes confer susceptibility to asthma and atopy in a Caucasian population.Semantic proximity Read ↗

IL-4 receptor genetic polymorphisms and asthma in Asian populations.Semantic proximity Read ↗

Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma.Semantic proximity Read ↗

Impact of interleukin 13 (IL13) genetic polymorphism Arg130Gln on total serum immunoglobulin (IgE) levels and interferon (IFN)-γ gene expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.