Article
Estrogen Inducibility of c-Ha-ras Transcription in Breast Cancer Cells
1 Oct 1999
Abstract excerpt
Although mutation of ras gene is rare in human breast cancer, overexpression of normal c-Ha-ras gene is frequently observed. Using a mouse mammary metastasis model consisting of genetically related mammary tumor sublines with variant metastatic potential, we have previously (i) demonstrated a direct correlation between c-Ha-ras mRNA and protein levels and metastatic potential and (ii) identified a novel...
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