A steroidogenic factor-1-binding site and cyclic adenosine 3',5'-monophosphate response element-like elements are required for the activity of the rat aromatase promoter in rat Leydig tumor cell lines.

doi:10.1210/endo.139.12.6377

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Article

A steroidogenic factor-1-binding site and cyclic adenosine 3',5'-monophosphate response element-like elements are required for the activity of the rat aromatase promoter in rat Leydig tumor cell lines.

Endocrinology - 1 Dec 1998

Young M, McPhaul M J

Abstract excerpt

Although transcription initiation within CYP19 (cytochrome P450 aromatase) occurs immediately 5' to the initiator methionine (proximal promoter) in two rat Leydig tumor cell lines (R2C and H540) that express high aromatase activity and in rat ovary, the patterns of aromatase expression in the two...

Topics

Animals
Aromatase
Base Sequence
Binding Sites
Cyclic AMP Response Element-Binding Protein
DNA-Binding Proteins
Electrophoresis, Polyacrylamide Gel
Fushi Tarazu Transcription Factors
Homeodomain Proteins
Leydig Cell Tumor
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Neoplasm Proteins

Nuclear Proteins

Promoter Regions, Genetic

Rats

Receptors, Cytoplasmic and Nuclear

Steroidogenic Factor 1

Source

Open in PubMed

Identifiers

PMID: 9832447
DOI: 10.1210/endo.139.12.6377

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9832447-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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