Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic element from human surfactant protein SP-C gene confers bronchiolar-alveolar cell specificity in transgenic mice

1 Oct 1991

Abstract excerpt

Transgenic mice bearing chimeric genes consisting of 5'-sequences derived from the human surfactant protein C (SP-C) gene and the bacterial chloramphenicol acetyltransferase (CAT) gene were generated. Analysis of CAT activity was utilized to demonstrate tissue-specific and developmental expression of chimeric genes containing 3.7 kb of sequences from the human SP-C gene. Lung-specific expression of the 3.7...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Infant Nutrition and Health
Share to Neonatal Respiratory Health Research
Share to Renal and related cancers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1928370
DOI: 10.1152/ajplung.1991.261.4.l349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic element from human surfactant protein SP-C gene confers bronchiolar-alveolar cell specificity in transgenic micePMID 1928370Read ↗

HumanSP-Cgene sequences that confer lung epithelium-specific expression in transgenic miceSemantic proximity Read ↗

Analysis of genomic regions involved in regulation of the rabbit surfactant protein A gene in transgenic mice.Semantic proximity Read ↗

cis-acting elements that confer lung epithelial cell expression of the CC10 gene.Semantic proximity Read ↗

Conditional Expression of Genes in the Respiratory Epithelium in Transgenic MiceSemantic proximity Read ↗

Conditional Expression of Fibroblast Growth Factor-7 in the Developing and Mature LungSemantic proximity Read ↗

Expression of a human surfactant protein C mutation associated with interstitial lung disease disrupts lung development in transgenic mice.Semantic proximity Read ↗

TTF-1 response element is critical for temporal and spatial regulation and necessary for hormonal regulation of human surfactant protein-A2 promoter activity.Semantic proximity Read ↗

rtTA toxicity limits the usefulness of the SP-C-rtTA transgenic mouse.Semantic proximity Read ↗

SP-A 3'-UTR is involved in the glucocorticoid inhibition of human SP-A gene expression.Semantic proximity Read ↗

Conditional Recombination Reveals Distinct Subsets of Epithelial Cells in Trachea, Bronchi, and AlveoliSemantic proximity Read ↗

Overexpression of surfactant protein-C mature peptide causes neonatal lethality in transgenic mice.Semantic proximity Read ↗

The variability in activity of the universally expressed human cytomegalovirus immediate early gene 1 enhancer/promoter in transgenic miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.