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Article

Human breast cancer progression can be regulated by dominant trans-acting factors in somatic cell hybridization studies.

Cancer research - 1 Aug 1996

Safarians S, Sternlicht M D, Yamanishi D T, Love S M, Barsky S H

Abstract excerpt

Human breast cancer is often characterized by a progression to an ER (estrogen receptor)-negative, estrogen-independent, antiestrogen-resistant, EGFR (epidermal growth factor receptor)-positive, and highly metastatic phenotype. The molecular and biochemical mechanisms behind this progression are not well defined. Most studies of breast cancer have focused on one or another aspect or this progression but have not...

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Identifiers

PMID: 8758927

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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