Article
The differential capacity of glucocorticoids and progestins to alter chromatin structure and induce gene expression in human breast cancer cells.
1 Sept 1994
Abstract excerpt
The T47D (A1-2) cell line is a human mammary carcinoma-derived cell line that has been engineered to constitutively express comparable levels of both glucocorticoid and progesterone receptors. In addition, these cells possess a stably integrated mouse mammary tumor virus (MMTV) luciferase reporter gene. Because the MMTV promoter is recognized similarly by both receptors, we have used this cell line to examine the...
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