Article
Transcriptional regulatory and response mapping of the rat Ha-ras upstream sequence using primary mammary epithelial cells.
Carcinogenesis - 1 Apr 1995
Ariazi E A, Thompson T A, Burkholder J K, Yang N S, Gould M N
Abstract excerpt
The rat Ha-ras upstream sequence (-2876 to +986 bp relative to the most 5' transcriptional start site) was transcriptionally mapped at a gross level. Ha-ras upstream sequence and 5' unidirectional deletion reporter constructs were transfected via particle bombardment into primary cultures of rat mammary epithelial cells. Analyses of Ha-ras reporter expression show that a fragment extending from -2876 to -2110 bp...
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