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Article

Relative power of linkage and transmission disequilibrium test strategies to detect non-HLA linked coeliac disease susceptibility genes.

Gut - 1 Nov 1999

Bevan S, Popat S, Houlston R S

Abstract excerpt

BACKGROUND: Susceptibility to coeliac disease is genetically determined by possession of specific HLA DQ alleles, acting in concert with one or more non-HLA linked genes. The pattern of familial risk is most parsimonious with a multiplicative model for the interaction between these two classes of genes. Haplotype sharing probabilities across the HLA region in affected sibling pairs suggest that genes within the...

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Identifiers

PMID: 10517901
DOI: 10.1136/gut.45.5.668
PMCID: PMC1727705

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Source receipt: pubmed, retrieved 7 Sept 2026.

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