Article
Linkage and association study of the CTLA-4 region in coeliac disease for Italian and Tunisian populations.
Tissue antigens - 1 Nov 1999
Clot F, Fulchignoni-Lataud M C, Renoux C, Percopo S, Bouguerra F, Babron M C, Djilali-Saiah I, Caillat-Zucman S, Clerget-Darpoux F, Greco L, Serre J L
Abstract excerpt
Coeliac disease (CD) is a multifactorial disease for which there is an intensive search for genetic risk factors. Some authors found an association between the CTLA-4 region and CD. In the present work, we investigate the possible implication of the CTLA-4 region as a genetic risk factor for CD, through two statistical approaches: the maximum likelihood score (MLS) test in a large Italian sample of affected...
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