Article
The first large population based twin study of coeliac disease.
Gut - 1 May 2002
Greco L, Romino R, Coto I, Di Cosmo N, Percopo S, Maglio M, Paparo F, Gasperi V, Limongelli M G, Cotichini R, D'Agate C, Tinto N, Sacchetti L, Tosi R, Stazi M A
Abstract excerpt
BACKGROUND AND AIMS: The genetic load in coeliac disease has hitherto been inferred from case series or anecdotally referred twin pairs. We have evaluated the genetic component in coeliac disease by estimating the concordance rate for the disease among twin pairs in a large population based study. METHODS: The Italian Twin Registry was matched with the membership lists of a patient support group. Forty seven twin...
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