Article
Regulation of bacteriophage lambda development by guanosine 5'-diphosphate-3'-diphosphate.
Virology - 30 Sept 1999
Slomińska M, Neubauer P, Wegrzyn G
Abstract excerpt
On infection of its host, Escherichia coli, bacteriophage lambda can follow one of two alternative developmental pathways: lytic or lysogenic. Here we demonstrate that the "lysis-versus-lysogenization" decision is influenced by guanosine tetraphosphate (ppGpp), a nucleotide that is synthesized in E. coli cells in response to amino acid or carbon source starvation. We found that the efficiency of lysogenization is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
