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Article

The guanosine nucleotide (p)ppGpp initiates development and A-factor production in myxococcus xanthus.

Genes & development - 1 Apr 1998

Harris B Z, Kaiser D, Singer M

Abstract excerpt

Guanosine 3'-di-5'-(tri)di-phosphate nucleotides [(p)ppGpp], synthesized in response to amino acid limitation, induce early gene expression leading to multicellular fruiting body formation in Myxococcus xanthus. A mutant (DK527) that fails to accumulate (p)ppGpp in response to starvation was found to be blocked in development prior to aggregation. By use of a series of developmentally regulated Tn5lac...

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Identifiers

PMID: 9531539
DOI: 10.1101/gad.12.7.1022
PMCID: PMC316683

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The guanosine nucleotide (p)ppGpp initiates development and A-factor production in myxococcus xanthus.PMID 9531539Read ↗

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