Article
Topoisomerase III is essential for accurate nuclear division in Schizosaccharomyces pombe.
Nucleic acids research - 15 Oct 1999
Goodwin A, Wang S W, Toda T, Norbury C, Hickson I D
Abstract excerpt
Topoisomerases catalyse changes in the topological state of DNA and are required for many aspects of DNA metabolism. While the functions of topoisomerases I and II in eukaryotes are well established, the role of topoisomerase III remains poorly defined. We have identified a gene in the fission yeast Schizosaccharomyces pombe, designated top3 (+), which shows significant sequence similarity to genes encoding...
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