Article
A functional polymorphism in the apolipoprotein B promoter that influences the level of plasma low density lipoprotein.
Journal of lipid research - 1 Sept 1999
van 't Hooft F M, Jormsjö S, Lundahl B, Tornvall P, Eriksson P, Hamsten A
Abstract excerpt
Apolipoprotein (apo) B is the structural protein moiety of plasma low density lipoprotein (LDL), an important risk factor for coronary heart disease (CHD). There is evidence that the rate of synthesis of apoB-containing lipoproteins may play an important role in the regulation of plasma LDL levels. However, it is generally thought that transcriptional regulation of the apoB gene is not a significant determinant...
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