Transcription efficiency of human apolipoprotein A-I promoter varies with naturally occurring A to G transition.

doi:10.1016/0014-5793(92)80597-a

Back to search

Article

Transcription efficiency of human apolipoprotein A-I promoter varies with naturally occurring A to G transition.

FEBS letters - 8 Jun 1992

Tuteja R, Tuteja N, Melo C, Casari G, Baralle F E

Abstract excerpt

In human, the gene coding for apolipoprotein A-I (apo A-I), a protein of the plasma lipid transport system, is expressed only in the liver and the intestine. A naturally occurring A to G substitution in the promoter at position -78 was shown to be associated with high density lipoproteins (HDL) i...

Topics

Adenine
Apolipoprotein A-I
Base Composition
Base Sequence
DNA
Guanine
Humans
Molecular Sequence Data
Mutation
Promoter Regions, Genetic
Transcription, Genetic
Transfection
Tumor Cells, Cultured

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.