Article
Association between the TaqIB polymorphism in the cholesteryl ester transfer protein gene locus and plasma lipoprotein levels in familial hypercholesterolemia.
Metabolism: clinical and experimental - 1 Jun 2001
Carmena-Ramón R, Ascaso J F, Real J T, Nájera G, Ordovás J M, Carmena R
Abstract excerpt
Cholesteryl ester transfer protein (CETP) facilitates the exchange of triglycerides (TG) and cholesteryl ester between lipoprotein particles. Subjects with familial hypercholesterolemia (FH) have been reported to have higher CETP activities, which could contribute to the lower high-density lipoprotein-cholesterol (HDL-C) levels and increased cardiovascular risk observed in some of these patients. Several...
Topics
- Adult
- Alleles
- Cardiovascular Diseases
- Carrier Proteins
- Cholesterol
- Cholesterol Ester Transfer Proteins
- Female
- Genotype
- Glycoproteins
- Humans
- Hyperlipoproteinemia Type II
- Lipoproteins
- Male
- Polymorphism, Genetic