The effect on transcription efficiency of the apolipoprotein AI gene of DNA variants at the 5' untranslated region.

doi:10.1007/s005990050051

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Article

The effect on transcription efficiency of the apolipoprotein AI gene of DNA variants at the 5' untranslated region.

International journal of clinical & laboratory research - 1 Jan 1998

Wang X L, Badenhop R B, Sim A S, Wilcken D E

Abstract excerpt

Elevated circulating levels of high-density lipoprotein and apolipoprotein AI are associated with reduced coronary artery disease risk. We have shown that a C to T substitution at +83 bp and a G to A substitution at -75 bp of the apolipoprotein AI gene are both related to increased high-density l...

Topics

5' Untranslated Regions
Alleles
Apolipoprotein A-I
Cells, Cultured
Cloning, Molecular
DNA Primers
Gene Expression
Genes, Reporter
Haplotypes
Humans
Liver
Luciferases
Polymorphism, Genetic
Promoter Regions, Genetic
Transcription, Genetic
Transfection

Source

Open in PubMed

Identifiers

PMID: 9879497
DOI: 10.1007/s005990050051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9879497-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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