Article
A novel cholesteryl ester transfer protein promoter polymorphism (-971G/A) associated with plasma high-density lipoprotein cholesterol levels. Interaction with the TaqIB and -629C/A polymorphisms.
Atherosclerosis - 1 Apr 2002
Le Goff Wilfried, Guerin Maryse, Nicaud Viviane, Dachet Christiane, Luc Gérald, Arveiler Dominique, Ruidavets J-B, Evans Alun, Kee Frank, Morrison Caroline, Chapman M John, Thillet Joëlle
Abstract excerpt
The plasma cholesteryl ester transfer protein (CETP) plays a key role in reverse cholesterol transport (RCT) by mediating the transfer of cholesteryl ester (CE) from high-density lipoprotein (HDL) to atherogenic ApoB-containing lipoproteins, including VLDL, IDL and LDL. We describe a new polymorphism located at position -971 in the human CETP gene promoter, which corresponds to a G/A substitution at a potential...
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