Article
Studies of apolipoprotein (a) promoter from subjects with different plasma lipoprotein (a) concentrations.
Clinical biochemistry - 1 Jun 2003
Wu June H, Lee I Neng
Abstract excerpt
OBJECTIVE: High plasma lipoprotein (a) [Lp(a)] level is closely related to coronary heart disease and cerebral thrombosis. The Lp(a) concentration is determined primarily by apolipoprotein (a) [apo(a)] gene and APO(a) mRNA abundance has been found to vary with apo(a) isoform. Our objective is to investigate whether APO(a) promoter activity is related to plasma Lp(a) level. DESIGN AND METHODS: The 5' 1.4 kilobases...
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