Article
Rapid detection of mutated E-cadherin in peritoneal lavage specimens from patients with diffuse-type gastric carcinoma.
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Jun 1999
Schuhmacher C, Becker K F, Reich U, Schenk U, Mueller J, Siewert J R, Höfler H
Abstract excerpt
Tumor cells in abdominal lavage specimens from patients with gastric carcinoma strongly predict subsequent peritoneal metastasis and poor prognosis. Reverse transcription (RT)-polymerase chain reaction (PCR) detection of wild-type E-cadherin has been claimed to be superior to conventional cytology for the detection of patients who subsequently develop peritoneal metastases. The present study tested this...
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