Article
Inactivation of the E-cadherin gene in primary gastric carcinomas and gastric carcinoma cell lines.
Japanese journal of cancer research : Gann - 1 Nov 1996
Tamura G, Sakata K, Nishizuka S, Maesawa C, Suzuki Y, Iwaya T, Terashima M, Saito K, Satodate R
Abstract excerpt
We investigated the E (epithelial)-cadherin gene for mutations and loss of heterozygosity (LOH) in 24 primary gastric carcinomas (12 differentiated and 12 undifferentiated types, including 3 signet-ring cell carcinomas), as well as 4 gastric carcinoma cell lines of the undifferentiated type (MKN-...
Topics
- Alleles
- Base Sequence
- Cadherins
- Carcinoma
- Exons
- Gene Deletion
- Gene Expression Regulation, Neoplastic
- Heterozygote
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
