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Article

Alpha-2-macroglobulin intronic polymorphism is not associated with autopsy-confirmed late-onset Alzheimer's disease.

Neuroscience letters - 24 Sept 1999

Kovács T, Cairns N J, Lantos P L

Abstract excerpt

Alpha-2-macroglobulin (A2M) intronic polymorphism has recently been reported to be associated with late-onset Alzheimer's disease (LOAD). To corroborate this association, we analysed the A2M and apolipoprotein E (APOE) polymorphisms in autopsy cases of the MRC Alzheimer's Disease Brain Bank, Institute of Psychiatry, London. The frequencies of the insertion and deletion alleles in AD were 0.81 and 0.19,...

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Source

Identifiers

PMID: 10505652
DOI: 10.1016/s0304-3940(99)00604-7

Genes

APOE

Provenance

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