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Article

Kinetic analysis of the actinorhodin aromatic polyketide synthase.

The Journal of biological chemistry - 27 Aug 1999

Dreier J, Shah A N, Khosla C

Abstract excerpt

Type II polyketide synthases (PKSs) are bacterial multienzyme systems that catalyze the biosynthesis of a broad range of natural products. A core set of subunits, consisting of a ketosynthase, a chain length factor, an acyl carrier protein (ACP) and possibly a malonyl CoA:ACP transacylase (MAT) forms a "minimal" PKS. They generate a poly-beta-ketone backbone of a specified length from malonyl-CoA derived building...

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Identifiers

PMID: 10455191
DOI: 10.1074/jbc.274.35.25108

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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