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Article

Evidence for a protein-protein interaction motif on an acyl carrier protein domain from a modular polyketide synthase.

Chemistry & biology - 1 Jun 2006

Weissman Kira J, Hong Hui, Popovic Bojana, Meersman Filip

Abstract excerpt

During biosynthesis on modular polyketide synthases (PKSs), chain extension intermediates are tethered to acyl carrier protein (ACP) domains through phosphopantetheinyl prosthetic groups. Each ACP must therefore interact with every other domain within the module, and also with a downstream acceptor domain. The nature of these interactions is key to our understanding of the topology and operation of these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16793520
DOI: 10.1016/j.chembiol.2006.04.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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