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Article

A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase.

Structure (London, England : 1993) - 4 Mar 2014

Gay Darren C, Gay Glen, Axelrod Abram J, Jenner Matthew, Kohlhaas Christoph, Kampa Annette, Oldham Neil J, Piel Jörn, Keatinge-Clay Adrian T

Abstract excerpt

The recently discovered trans-acyltransferase modular polyketide synthases catalyze the biosynthesis of a wide range of bioactive natural products in bacteria. Here we report the structure of the second ketosynthase from the bacillaene trans-acyltransferase polyketide synthase. This 1.95 Å resolution structure provides the highest resolution view available of a modular polyketide synthase ketosynthase and reveals...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24508341
DOI: 10.1016/j.str.2013.12.016
PMCID: PMC3966118

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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