Article
The potential of various HIV-1 mutants to inhibit the replication of wild-type virus.
Biochemical and biophysical research communications - 18 Jun 1998
Inubushi R, Shimano R, Oshima Y, Adachi A
Abstract excerpt
We have previously demonstrated that many of gag mutants of human immunodeficiency virus type 1 (HIV-1) inhibited the replication of wild-type (wt) HIV-1. In this study, various HIV-1 mutants were systematically analyzed with respect to their ability to suppress the replication of wt HIV-1. Sixteen mutants of all eight HIV-1 genes other than gag were evaluated for their inhibitory effects. Only an env mutant...
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