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Article

The H9/M8166 tropism of various HIV-1 mutants is determined by distinct cellular factors (review).

International journal of molecular medicine - 1 Mar 2000

Yoshida A, Shimomoto J, Koh K B, Fujita M, Adachi A

Abstract excerpt

We have previously shown that a number of human immunodeficiency virus type 1 (HIV-1) mutants generated in vitro display a replication-defect in a cell-dependent manner. Of the mutants of this category, those of gag, vif, and env mutants do not grow at all in lymphocytic H9 (non-permissive) cells, but quite well in M8166 (permissive) cells. To determine whether the cell-dependent growth of the mutants is...

Topics

Animals
HIV-1
Humans
Lymphocytes
Mutation
Tumor Cells, Cultured
Virus Replication

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 10677572
DOI: 10.3892/ijmm.5.3.291

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