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Article

Activation of beta-catenin in epithelial and mesenchymal hepatoblastomas.

Oncogene - 27 Jan 2000

Wei Y, Fabre M, Branchereau S, Gauthier F, Perilongo G, Buendia M A

Abstract excerpt

Wnt/beta-catenin signaling is frequently activated in cancer cells by stabilizing mutations of beta-catenin or loss-of-function mutations of the APC tumor suppressor gene. We have analysed the role of beta-catenin in the pathogenesis of hepatoblastoma (HB), an embryonic liver tumor occurring main...

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Source

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PMID: 10698519
DOI: 10.1038/sj.onc.1203356

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-10698519-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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