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Article

P53 mutation as a source of aberrant beta-catenin accumulation in cancer cells.

Oncogene - 14 Nov 2002

Cagatay Tolga, Ozturk Mehmet

Abstract excerpt

beta-catenin is involved in both cell-cell interactions and wnt pathway-dependent cell fate determination through its interactions with E-cadherin and TCF/LEF transcription factors, respectively. Cytoplasmic/nuclear levels of beta-catenin are important in regulated transcriptional activation of T...

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Share to beta Catenin
Share to Cytoskeletal Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Liver Neoplasms

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Share to Tumor Cells, Cultured

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 12439747
DOI: 10.1038/sj.onc.1205919

Genes

APC
CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12439747-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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