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Article

Energetics and cooperativity of tertiary hydrogen bonds in RNA structure.

Biochemistry - 6 Jul 1999

Silverman S K, Cech T R

Abstract excerpt

Tertiary interactions that allow RNA to fold into intricate three-dimensional structures are being identified, but little is known about the thermodynamics of individual interactions. Here we quantify the tertiary structure contributions of individual hydrogen bonds in a "ribose zipper" motif of the recently crystallized Tetrahymena group I intron P4-P6 domain. The 2'-hydroxyls of P4-P6 nucleotides C109/A184 and...

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Source

Identifiers

PMID: 10393544
DOI: 10.1021/bi9906118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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