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Article

Molecular and cellular basis of the altered immune response against arsonate in irradiated A/J mice autologously reconstituted.

International immunology - 1 Jul 1999

Ismaïli J, Razanajaona D, Van Acker A, Wuilmart C, Mancini I, Heinen E, Leo O, Lebecque S, Urbain J, Brait M

Abstract excerpt

The humoral immune response to arsonate (Ars) in normal A/J mice is dominated in the late primary and particularly in the secondary response by a recurrent and dominant idiotype (CRIA) which is encoded by a single canonical combination of the variable gene segments: VHidcr11-DFL16.1-JH2 and Vkappa10-Jkappa1. Accumulation of somatic mutations within cells expressing this canonical combination or some less frequent...

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Identifiers

PMID: 10383949
DOI: 10.1093/intimm/11.7.1157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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