Article
TCR diversity of H60-specific CD8 T cells during the response evolution and influence of CD4 help.
Transplantation - 15 Jun 2009
Choi Jung Hwa, Ryu Su Jeong, Jung Kyung Min, Kim Sol, Chang Jun, Kim Tae Woo, Choi Eun Young
Abstract excerpt
BACKGROUND: H60 is a hematopoietic cell-specific dominant minor histocompatibility antigen that is considered to be ideal for modeling leukemia treatment after bone-marrow transplantation. We characterized the H60-specific CD8 T-cell response as CD4 help dependent. This study investigated the T-cell receptor (TCR) repertoires during the evolution of H60-specific CD8 T-cell responses and influence of CD4 help on...
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