Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contrasting the in situ behavior of a memory B cell clone during primary and secondary immune responses.

Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 1999

Vora K A, Tumas-Brundage K, Manser T

Abstract excerpt

Whether memory B cells possess altered differentiative potentials and respond in a qualitatively distinct fashion to extrinsic signals as compared with their naive precursors is a current subject of debate. We have investigated this issue by examining the participation of a predominant anti-arsonate clonotype in the primary and secondary responses in the spleens of A/J mice. While this clonotype gives rise to few...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibody-Producing Cells
Share to Arsenicals
Share to Germinal Center

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Haptens

Share to Immunization

Share to Immunization, Secondary

Share to Mice, Inbred A

Share to Mollusca

Source

Identifiers

PMID: 10510371

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contrasting the in situ behavior of a memory B cell clone during primary and secondary immune responses.PMID 10510371Read ↗

Defining subsets of naive and memory B cells based on the ability of their progeny to somatically mutate in vitro.Semantic proximity Read ↗

Germinal center-dependent and -independent memory B cells produced throughout the immune response.Semantic proximity Read ↗

Restricted Clonality and Limited Germinal Center Reentry Characterize Memory B Cell Reactivation by BoostingSemantic proximity Read ↗

Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memorySemantic proximity Read ↗

Development and maintenance of a B220- memory B cell compartment.Semantic proximity Read ↗

Tracing the development of single memory-lineage B cells in a highly defined immune response.Semantic proximity Read ↗

Early appearance of germinal center-derived memory B cells and plasma cells in blood after primary immunization.Semantic proximity Read ↗

Both mutated and unmutated memory B cells accumulate mutations in the course of the secondary response and develop a new antibody repertoire optimally adapted to the secondary stimulus.Semantic proximity Read ↗

Antigen-driven B cell differentiation in vivo.Semantic proximity Read ↗

Clonal redemption and clonal anergy as mechanisms to balance B cell tolerance and immunitySemantic proximity Read ↗

Memory in the B–cell compartment: antibody affinity maturationSemantic proximity Read ↗

Canonical germinal center B cells may not dominate the memory response to antigenic challenge.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.