Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhancement of TBP binding by activators and general transcription factors.

Nature - 10 Jun 1999

Li X Y, Virbasius A, Zhu X, Green M R

Abstract excerpt

Eukaryotic transcriptional activators function, at least in part, by promoting assembly of the preinitiation complex, which comprises RNA polymerase II and its general transcription factors (GTFs). Activator-mediated stimulation of the assembly of the preinitiation complex has been studied in vitro but has been relatively refractory to in vivo analysis. Here we use a DNA-crosslinking/immunoprecipitation assay to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Footprinting
Share to Formaldehyde
Share to Mediator Complex

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to TATA-Binding Protein Associated Factors

Share to TATA Box

Share to TATA-Box Binding Protein

Share to Transcription Factor TFIIB

Share to Transcription Factor TFIID

Source

Identifiers

PMID: 10376604
DOI: 10.1038/21232

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhancement of TBP binding by activators and general transcription factors.PMID 10376604Read ↗

TATA-binding protein variants that bypass the requirement for Mot1 in vivo.Semantic proximity Read ↗

Genome-wide transcriptional dependence on conserved regions of Mot1.Semantic proximity Read ↗

Regulation of TATA-binding protein dynamics in living yeast cells.Semantic proximity Read ↗

Regulation of rRNA synthesis by TATA-binding protein-associated factor Mot1.Semantic proximity Read ↗

Connecting a promoter-bound protein to TBP bypasses the need for a transcriptional activation domain.Semantic proximity Read ↗

Interconversion between active and inactive TATA-binding protein transcription complexes in the mouse genome.Semantic proximity Read ↗

Transcriptional corepression in vitro: a Mot1p-associated form of TATA-binding protein is required for repression by Leu3p.Semantic proximity Read ↗

Downstream promoter interactions of TFIID TAFs facilitate transcription reinitiation.Semantic proximity Read ↗

TBP-associated factors are not generally required for transcriptional activation in yeast.Semantic proximity Read ↗

Intermediates in formation and activity of the RNA polymerase II preinitiation complex: holoenzyme recruitment and a postrecruitment role for the TATA box and TFIIB.Semantic proximity Read ↗

Analysis of TFIIA function In vivo: evidence for a role in TATA-binding protein recruitment and gene-specific activation.Semantic proximity Read ↗

A role for activator-mediated TFIIB recruitment in diverse aspects of transcriptional regulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.