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Article

Interconversion between active and inactive TATA-binding protein transcription complexes in the mouse genome.

Nucleic acids research - 1 Feb 2012

Choukrallah Mohamed-Amin, Kobi Dominique, Martianov Igor, Pijnappel W W M Pim, Mischerikow Nikolai, Ye Tao, Heck Albert J R, Timmers H Th Marc, Davidson Irwin

Abstract excerpt

The TATA binding protein (TBP) plays a pivotal role in RNA polymerase II (Pol II) transcription through incorporation into the TFIID and B-TFIID complexes. The role of mammalian B-TFIID composed of TBP and B-TAF1 is poorly understood. Using a complementation system in genetically modified mouse cells where endogenous TBP can be conditionally inactivated and replaced by exogenous mutant TBP coupled to tandem...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22013162
DOI: 10.1093/nar/gkr802
PMCID: PMC3287176

Genes

TBP
BTAF1
TAF1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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