Article
Genome-wide transcriptional dependence on conserved regions of Mot1.
Molecular and cellular biology - 1 Jun 2011
Venters Bryan J, Irvin Jordan D, Gramlich Paul, Pugh B Franklin
Abstract excerpt
TATA binding protein (TBP) plays a central role in transcription complex assembly and is regulated by a variety of transcription factors, including Mot1. Mot1 is an essential protein in Saccharomyces cerevisiae that exerts both negative and positive effects on transcription via interactions with TBP. It contains two conserved regions important for TBP interactions, another conserved region that hydrolyzes ATP to...
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