Article
Regulation of TATA-binding protein dynamics in living yeast cells.
Proceedings of the National Academy of Sciences of the United States of America - 9 Sept 2008
Sprouse Rebekka O, Karpova Tatiana S, Mueller Florian, Dasgupta Arindam, McNally James G, Auble David T
Abstract excerpt
Although pathways for assembly of RNA polymerase (Pol) II transcription preinitiation complexes (PICs) have been well established in vitro, relatively little is known about the dynamic behavior of Pol II general transcription factors in vivo. In vitro, a subset of Pol II factors facilitates reinitiation by remaining very stably bound to the promoter. This behavior contrasts markedly with the highly dynamic...
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