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Article

Transcriptional corepression in vitro: a Mot1p-associated form of TATA-binding protein is required for repression by Leu3p.

Molecular and cellular biology - 1 Apr 1996

Wade P A, Jaehning J A

Abstract excerpt

Signals from transcriptional activators to the general mRNA transcription apparatus are communicated by factors associated with RNA polymerase II or the TATA-binding protein (TBP). Currently, little is known about how gene-specific transcription repressors communicate with RNA polymerase II. We have analyzed the requirements for repression by the saccharomyces cerevisiae Leu3 protein (Leu3p) in a reconstituted...

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Identifiers

PMID: 8657139
DOI: 10.1128/MCB.16.4.1641
PMCID: PMC231150

Genes

TBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional corepression in vitro: a Mot1p-associated form of TATA-binding protein is required for repression by Leu3p.PMID 8657139Read ↗

Genome-wide transcriptional dependence on conserved regions of Mot1.Semantic proximity Read ↗

Evidence that Spt3 functionally interacts with Mot1, TFIIA, and TATA-binding protein to confer promoter-specific transcriptional control in Saccharomyces cerevisiae.Semantic proximity Read ↗

The NOT, SPT3, and MOT1 genes functionally interact to regulate transcription at core promoters.Semantic proximity Read ↗

Identification and analysis of Mot3, a zinc finger protein that binds to the retrotransposon Ty long terminal repeat (delta) in Saccharomyces cerevisiae.Semantic proximity Read ↗

Regulation of rRNA synthesis by TATA-binding protein-associated factor Mot1.Semantic proximity Read ↗

Alternative outcomes in assembly of promoter complexes: the roles of TBP and a flexible linker in placing TFIIIB on tRNA genes.Semantic proximity Read ↗

Yeast regulatory protein LEU3: a structure-function analysis.Semantic proximity Read ↗

Enhancement of TBP binding by activators and general transcription factors.Semantic proximity Read ↗

Yeast SUB1 is a suppressor of TFIIB mutations and has homology to the human co-activator PC4.Semantic proximity Read ↗

Interplay of TBP inhibitors in global transcriptional control.Semantic proximity Read ↗

A new regulatory domain on the TATA-binding protein.Semantic proximity Read ↗

Connecting a promoter-bound protein to TBP bypasses the need for a transcriptional activation domain.Semantic proximity Read ↗

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